Tiny Perfusion Letter #775

Tiny Perfusion Letter

We have been busy

Apologies for having you wait for your favorite newsletter 🫣 We can only imagine the agony and fearful checking of your inbox or Substack feed… Will it arrive today…? How much longer do we have to wait to feed our brain…? Just kidding, you’re probably thinking - finally, a few weeks without the pressure to keep up!! (for the new subscribers, no worries, this length of the “Tiny” Perfusion Letter is not the usual…)

Your patience has been worth it. Here is our extra long TPL, filled to the brim with the latest and (perhaps not always) greatest on perfusion, cardiac surgery and all that comes with it.

Like surveys… 😌 This one only takes 5 minutes and aims to capture current practices in anticoagulation, heparin‑protamine management, and blood conservation techniques during adult cardiopulmonary bypass usage. Your insight - drawn from daily clinical experience - will help us map international variability, identify areas for quality improvement, and provide a foundation for future collaborative research.

#enjoyandshare

Analysis of 2024 EACTS/EACTAIC/EBCP Guidelines on Cardiopulmonary Bypass in Adult Cardiac Surgery.

Ripoll JG, Bittner EA, Zaremba S, Nabzdyk CS, Seelhammer TG et al.

J Cardiothorac Vasc Anesth. 2025 Mar 31. Online ahead of print

Extracorporeal Therapies in the Emergency Room and Intensive Care Unit.

Londoño L.

Vet Clin North Am Small Anim Pract. 2025 May;55(3):525-537

Managing Coagulation Using the Sonoclot Analyzer in Patients With Disseminated Intravascular Coagulation.

Wan P, Geng Y, Su L, Liu J, Tong H et al.

Am J Crit Care. 2025 May 1;34(3):194-207

A Heart Full of Nails: Complex Management of Multiple Nail Gun Cardiac Injuries.

Abid S, Stolear A, Zarich S.

Eur Heart J Case Rep. 2025 Apr 8;9(4):ytaf168 OPEN ACCESS

Effects of Inhaled Anaesthetic Agents on the Oxygen Dissociation Curve: An Updated Discussion.

Kumar A, N M.

J Perioper Pract. 2025 Feb 24. Online ahead of print

Electroencephalogram Monitoring during Anesthesia and Critical Care: a Guide for the Clinician.

Manohara N, Ferrari A, Greenblatt A, Berardino A, Peixoto C et al.

J Clin Monit Comput. 2025 Apr;39(2):315-348

Long-term Risk for Incident Cancer in Patients undergoing Coronary Artery Bypass Grafting with or without Cardiopulmonary Bypass: a Nationwide Population-based Study.

Mennander A, Nielsen SJ, Skyttä T, Landenhed Smith M, Martinsson A et al.

Eur J Cardiothorac Surg. 2025 Mar 28;67(4):ezaf110 OPEN ACCESS

Safety and Limitations of Line Pressure-targeted Cerebral Perfusion Strategy in Aortic Arch Surgery.

Jung JC, Chang HW, Lee JH, Park KH.

Eur J Cardiothorac Surg. 2025 Mar 28;67(4):ezaf131

Vasoplegic Syndrome in Cardiac Surgery: Bridging Therapeutic Gaps with Best Practices and Future Research.

Unic-Stojanovic D, Koster A, Erdoes G, Milojevic M.

Interdiscip Cardiovasc Thorac Surg. 2025 Mar 29;40(4):ivaf075 OPEN ACCESS

Impact of Psycho-educational Interventions on Patients undergoing Coronary Artery Bypass Grafting Surgery.

Bagheri S, Dadashpouromrani Z, Setoodeh G, Shirazi ZH, Amiri A, Ghobadimoghaddam R.

J Cardiothorac Surg. 2025 Apr 30;20(1):223 OPEN ACCESS

Patient Perspectives on Surgical Handover Quality: a Mixed-methods Survey.

Ryan JM, Tomlinson P, Simiceva A, Kavanagh DO, Eppich W et al.

Patient Saf Surg. 2025 May 2;19(1):14 OPEN ACCESS

Risk Factors for Postoperative Hypothermia in Non-cardiac Surgery Patients: a Systematic Review and Meta-analysis.

Tan R, Chen Y, Yang D, Long X, Ma H, Yang C.

BMC Anesthesiol. 2025 Apr 30;25(1):223 OPEN ACCESS

Procalcitonin as a Biomarker for Postoperative Pneumonia: a Study on Dynamics following Cardiopulmonary Bypass in Adults.

Mao GX, Wang LY, Chen WS, Zhao S, Shao YF et al.

BMC Cardiovasc Disord. 2025 Apr 30;25(1):338 OPEN ACCESS

Enhanced Recovery in Cardiac Surgery Patients with Frailty through Comprehensive Perioperative Nursing Interventions: A Randomized Controlled Trial.

Jin N, Gu T, Song S, Yao J, Pang X.

Clin Rehabil. 2025 May;39(5):632-645 OPEN ACCESS

A Non-intrusive, Non-obstructive, Versatile Venous Reservoir Blood Volume Sensor Based on Computer Vision for Clinical Cardiopulmonary Bypass.

Kaddis R, Chung CJ, Murtha S, Jiang H

IEEE Sensors Letters 2025 May;9(5):1-4

Changing Minds, Saving Lives: How Training Psychological Safety Transforms Healthcare.

Vu V, Buléon C, Le TA, Lua CCP, Martin F et al.

BMJ Open Qual. 2025 May 2;14(2):e003186 OPEN ACCESS

Acid-Base Status in Critically Ill Patients: Physicochemical vs. Traditional Approach.

Ciabattoni A, Chiumello D, Mancusi S, Pozzi T, Monte A et al.

J Clin Med. 2025 May 6;14(9):3227 OPEN ACCESS

Nociceptive and Non-nociceptive Pain in Critical Care Patients after Cardiac Surgery.

Yaman Aktas Y, Özkan E.

J Perioper Pract. 2025 Apr 30. Online ahead of print

Safe and Easy Inferior Vena Cava Snaring and Suction Tube Placement Using a Silicon Drain Tube During Minimally Invasive Cardiac Surgery.

Takei Y, Saito S, Tsuchiya G, Kuwata T, Shibasaki I, Fukuda H.

Innovations (Phila). 2025 May 5. Online ahead of print

Active Chest Tube Clearance Added to an Enhanced Recovery After Cardiac Surgery (ERAS) Program Improves Outcomes and Reduces Resource Utilization.

Gerdisch MW, Johns C, Parikshak M, Barksdale A, Perrault LP.

Innovations (Phila). 2025 Mar-Apr;20(2):194-200

Maintaining Ventilation with Very Low Tidal Volume and Positive-end Expiratory Pressure Versus No Ventilation during Cardiopulmonary Bypass for Cardiac Surgery in Adults: a Randomized Clinical Trial.

Tadié JM, Ouattara A, Laviolle B, Lesouhaitier M, Esvan M et al.

Intensive Care Med. 2025 May;51(5):849-860 OPEN ACCESS

Micro-nanoplastic Induced Cardiovascular Disease and Dysfunction: a Scoping Review.

Goldsworthy A, O'Callaghan LA, Blum C, Horobin J, Tajouri L et al.

J Expo Sci Environ Epidemiol. 2025 Apr 1. Online ahead of print OPEN ACCESS

Prognostic Value of Perioperative Near-Infrared Spectroscopy Monitoring for Postoperative Acute Kidney Injury in Pediatric Cardiac Surgery: A Systematic Review.

Niezen CK, Modestini M, Massari D, Bos AF, Scheeren TWL et al.

Semin Cardiothorac Vasc Anesth. 2025 Feb 10. Online ahead of print OPEN ACCESS

Deep Insight Into Cytokine Storm: from Pathogenesis to Treatment.

Nie J, Zhou L, Tian W, Liu X, Yang L et al.

Signal Transduct Target Ther. 2025 Apr 16;10(1):112 OPEN ACCESS

Characterizing Thrombus Adhesion Strength on Common Cardiovascular Device Materials.

Kannojiya V, Almasy SE, Monclova JL, Contreras J, Costanzo F, Manning KB.

Front Bioeng Biotechnol. 2024 Aug 14;12:1438359 OPEN ACCESS

A Machine Learning-Based Clustering Analysis to Explore Bisphenol A and Phthalate Exposure from Medical Devices in Infants with Congenital Heart Defects.

Chou WC, Gaynor JW, Graham EM, Klepczynski B, Walker T et al.

Environ Health Perspect. 2025 May 8. Online ahead of print OPEN ACCESS

Noteworthy Literature in 2024 Editorial Charting Progress: A Year of Advances in Cardiac Surgery, Transplantation, and Anesthetic Management.

Littlejohn J, Kertai MD, Abrams B, Weitzel N.

Semin Cardiothorac Vasc Anesth. 2025 Jun;29(2):97-102 OPEN ACCESS

Development, Validation, and Clinical Evaluation of a Machine-learning Based Model for Diagnosing Early Infection after Cardiovascular Surgery (DEICS): a Multi-center Cohort Study.

Pan T, Zhang H, Wang C, Wang H, Matniyaz Y et al.

Int J Surg. 2025 Apr 1;111(4):2862-2871 OPEN ACCESS

Reducing Greenhouse Gas Emissions and Modifying Nitrous Oxide Delivery at Stanford: Observational, Pilot Intervention Study.

Kraybill EP, Chen D, Khan S, Kalra P.

JMIR Perioper Med. 2025 Jan 9;8:e64921 OPEN ACCESS

Perioperative Management of Adult Patients Undergoing Coronary Artery Bypass Grafting and Valve Surgery: a Literature Review.

Vasconcelos NNB, Queiroz VNF, Souza GM, Mangini S, Silva FMF et al.

Einstein (Sao Paulo). 2025 May 2;23:eRW1353 OPEN ACCESS

Alteration in Indole Metabolites After Cardiopulmonary Bypass Surgery in Neonates and Infants.

Leroue MK, Maddux AB, Lehmann T, Niemiec S, Mancuso CA et al.

Crit Care Explor. 2025 May 5;7(5):e1267

The Value of Cerebral and Somatic Near-infrared Spectroscopy within an Integrated Tissue Perfusion Monitoring Strategy in Cardiac Surgery: A Prospective Pilot Study.

Antonitsis P, Argiriadou H, Gkiouliava A, Deliopoulos A, Mimikos S et al.

Perfusion. 2025 May 8. Online ahead of print

Goal Directed Perfusion (GDP) Strategy: DO₂-target is Not the Final Goal.

Wang T, Wang J, Zhang H, Zhang J, Ji B.

J Clin Anesth. 2025 May 8;104:111862. Online ahead of print

Is Surgical Smoke a Relevant Contamination for Salvaged Autologous Blood? A Pilot Study.

Stadlbauer A, Fiedler P, Tuemmler S, Gruber M, Schmid C, Seyfried TF.

Vox Sang. 2025 May 4. Online ahead of print

Comparison of Two Different Autotransfusion Devices: An Ex-vivo Study.

Deventer SVD, Stehouwer MC, van Oeveren W.

Perfusion. 2025 May 7. Online ahead of print

Acute Ischemic and Hemorrhagic Cerebrovascular Strokes After Cardiac Surgery: Incidence, Predictors, and Outcomes.

Laimoud M, Alanazi MN, Machado P, Maghirang MJ, Althibait S et al.

Crit Care Res Pract. 2025 Apr 30;2025:6645363 OPEN ACCESS

Standardizing Protamine Dosage in Cardiac Surgery.

Taneja R.

J Cardiothorac Vasc Anesth. 2025 Jun;39(6):1610

Association of Oxygenation Targets and Mortality in Critical Care Patients Following Cardiac Surgery: A Retrospective Cohort Study.

Jiang Z, Shan Y, Wei Y, Luo T.

J Cardiothorac Vasc Anesth. 2025 Jun;39(6):1506-1513

Effect of Dexmedetomidine on Cerebrovascular Carbon Dioxide Reactivity During Pediatric Cardiac Surgery With Cardiopulmonary Bypass.

Sun L, Zhang K, Wang H, Ji W, Huang Y et al.

J Cardiothorac Vasc Anesth. 2025 Jun;39(6):1482-1488

The Next Wave: Are We Prepared for Patients on Anticoagulation With Factor XI Inhibitors in Cardiac Surgery?

Erdoes G, Koster A, Steiner ME.

J Cardiothorac Vasc Anesth. 2025 Jun;39(6):1361-1364

Comparative Analysis of Routine Clinical Debriefings and Incident Reports: Insights for Patient Safety and Teamwork Enhancement.

Paquay M, Kolbe M, Klenkenberg S, Buléon C, Bertrand A et al.

Int J Qual Health Care. 2025 Feb 18;37(1):mzaf010

Validation and Optimization of a Blood Transfusion Prediction Model for Low Transfusion Rate Adult Cardiac Surgery.

Haumann R, Plonek T, Niesten E, Maaskant J, Arens J et al.

Perfusion. 2025 Apr 19. Online ahead of print

Pharmacokinetics and Pharmacodynamics of Analgesic and Anesthetic Drugs in Patients During Cardiac Surgery With Cardiopulmonary Bypass: A Narrative Review.

Beukers A, Breel J, van den Brom C, Saatpoor A, Kluin J et al.

Anesth Analg. 2025 May 16. Online ahead of print OPEN ACCESS

A Novel Blood Volume Monitoring Approach in a Venous Reservoir Using a Laser Displacement Sensor for Blood Surface Distance Measurement.

Fukuhara S, Yamamoto KI.

J Artif Organs. 2025 May 16. Online ahead of print

Combining Procalcitonin, c-reactive Protein, and White Blood Cell Count in Predicting Infections in Pediatric Open Cardiac Surgery with Cardiopulmonary Bypass.

Ha TM, Tran MM, Le TV, Phung NTN.

J Pediatr (Rio J). 2025 May 17. Online ahead of print OPEN ACCESS

A Prospective Non-inferiority Trial of Pathogen Reduced Platelets Compared to Non-pathogen Reduced Platelets for Correction of Viscoelastic Platelet Function Testing in Cardiac Surgery.

Fontaine MJ, Lasola JJM, Martinez-Hernandez A, Marshall JN, Bentzen S et al.

Transfusion. 2025 May 15. Online ahead of print OPEN ACCESS

Achieving Neuroprotection in the Setting of Early Extubation During Infant Cardiac Surgery: A Prospective, Randomized, and Blinded Study.

Naguib AN, Bozych M, McNally K, Galantowicz M, Tobias J.

Cardiol Res. 2025 Jun;16(3):178-188 OPEN ACCESS

Intraoperative Assessment of Cerebral Autoregulation With Cerebral Oximetry Index in Neonates Undergoing Cardiac Surgery: A Pilot Study.

Pezzato S, Govindan RB, Beqiri E, Smielewski P, Waberski A et al.

J Cardiothorac Vasc Anesth. 2025 Apr 18. Online ahead of print

Outcomes of a Standardized Protocol on the Management of Acute Type A Aortic Dissection: A Retrospective Cohort Study.

Philippoz S, Adamopoulos D, Sologashvili T, Steenberghe MV, Jolou J et al.

Aorta (Stamford). 2025 May 13. Online ahead of print OPEN ACCESS

Intranasal Insulin Enhances Postoperative Sleep Quality and Delirium in Middle-aged Cardiac Surgery Patients: A Randomized Controlled Trial.

Yang M, Lu T, Cao L, Xiao C, Liang Y et al.

Sleep Med. 2025 May 10;132:106560. Online ahead of print