Tiny Perfusion Letter #616
Tiny Perfusion Letter
On August 1, 1916, in the midst of the first world war,
a second-year medical student at Johns Hopkins
published his discovery that 'cephalin' derived from the liver,
so-called 'heparphosphatide', was able to anticoagulate blood
He thought he had discovered antithrombin, but it was in fact heparin
In 1957, he described his journey towards the discovery,
but the article was only published in 1959, cut abruptly short,
due to his passing during the writing
Remarkable stories, from more than 100 years ago
We're still using heparin and talking about it
Perhaps we should make August 1, "Heparin Day"
#enjoyandshare
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The Predictive Value of the 4Ts and HEP Score at Recommended Cutoffs in Patients With Mechanical Circulatory Support Devices.
Kram SJ, Hamidi A, Kram BL, Arepally G, Levy JH.
J Cardiothorac Vasc Anesth. 2022 Jul;36(7):1873-1879
Cannulas and Cannulation Options for Minimally Invasive Surgery.
Newman JS, Patel NC.
Innovations (Phila). 2022 Mar-Apr;17(2):76-82 OPEN ACCESS
Measuring the Resting Energy Expenditure in Children on Extracorporeal Membrane Oxygenation: A Prospective Pilot Study.
Ewing LJ, Domico MB, Ramirez R, Starr JP, Lam DR, Mink RB.
ASAIO J. 2022 Apr 22. Online ahead of print
Effect Of Aortic Cannulation Depth on Air Emboli Transport during Cardiopulmonary Bypass: A Computational Study.
Ho R, McDonald C, Pauls JP, Li Z.
Perfusion. 2022 May 21. Online ahead of print
A Prospective Observational Study on the Effect of Emboli Exposure on Cerebral Autoregulation in Cardiac Surgery Requiring Cardiopulmonary Bypass.
Jabur GN, Merry AF, McGeorge A, Cavadino A, Donnelly J, Mitchell SJ.
Perfusion. 2022 May 21. Online ahead of print
Trends, Advantages and Disadvantages in Combined Extracorporeal Lung and Kidney Support From a Technical Point of View.
Martins Costa A, Halfwerk F, Wiegmann B, Neidlin M, Arens J.
Front Med Technol. 2022 Jun 21;4:909990 OPEN ACCESS
Effect of Nitric Oxide via Cardiopulmonary Bypass on Ventilator-Free Days in Young Children Undergoing Congenital Heart Disease Surgery: The NITRIC Randomized Clinical Trial.
Schlapbach LJ, Gibbons KS, Horton SB, Johnson K, Long DA et al.; NITRIC Study Group, the Australian and New Zealand Intensive Care Society Clinical Trials Group (ANZICS CTG), and the ANZICS Paediatric Study Group (PSG).
JAMA. 2022 Jul 5;328(1):38-47 OPEN ACCESS
Ten Overlooked Mistakes During Early Mobilisation in the Intensive Care Unit.
Gómez-González A, Martínez-Camacho MA, Jones-Baro RA, Gallardo A, Saavedra SN, Teixeira da Cruz AG.
ICU Management & Practice. 2022; 22(3): 146-149 OPEN ACCESS
Effect of Intraoperative Handovers of Anesthesia Care on Mortality, Readmission, or Postoperative Complications Among Adults: The HandiCAP Randomized Clinical Trial.
Meersch M, Weiss R, Küllmar M, Bergmann L, Thompson A et al.
JAMA. 2022 Jun 28;327(24):2403-2412 OPEN ACCESS
Key Characteristics Impacting Survival of COVID-19 Extracorporeal Membrane Oxygenation.
Herrmann J, Lotz C, Karagiannidis C, Weber-Carstens S, Kluge S et al.; German ECMO COVID Study Group.
Crit Care. 2022 Jun 28;26(1):190 OPEN ACCESS